1. Mekhoa e mecha ea ho lemoha theknoloji
Nts'etsopele ea mekhoa e nepahetseng le e sebetsang ea ho lemoha e ntse e le sebaka sa bohlokoa lipatlisisong tsa sodium cyclamate, e bapala karolo ea bohlokoa taolong ea polokeho ea lijo.
Setšoantšo sa Hyperspectral se Kopantsoeng le Thuto ea Mochini:
Phuputso ea 2025 e hlahisitse mokhoa oa ho lemoha ka potlako le o sa senyeheng. Mokhoa ona o sebelisa near-infrared hyperspectral imaging (NIR-HSI, 1000–1700 nm) ho hlahloba phofo ea lijo tsa katse 'me o kenyelletsa lik'hemik'hale le li-algorithms tsa ho ithuta ka mochini (mohlala, mehlala ea partial least squares regression (PLSR) e sebetsitsoeng pele ka Savitzky-Golay smoothing) ho fihlela tlhahlobo ea bongata ea sodium saccharin e ekelitsoeng ka molao esita le li-sweeteners tse ling. Ho tlalehoa hore mohlala ona o fihletse coefficient of determination ea ho bolela esale pele (R²) e phahameng ho fihlela ho 0.98 le phoso ea root mean square of prediction (RMSEP) ea 0.22 wt%. Sena se fana ka sesebelisoa se secha se matla bakeng sa ho lekola boleng ba inthanete ba lijo tsa liphoofolo tse ruuoang lapeng le matrices e meng e rarahaneng ea lijo.
Ho kopanngoa ha Maemo a ka Hare a Isotope a Tsitsitseng:
Ho ntlafatsa ho nepahala le ho hanyetsa ho kena-kenana ha ho lemoha bongata ba spectrometric, bafuputsi ba ile ba etsa deuterium-labeled sodium cyclamate (sodium cyclamate e tsitsitseng e nang le D) e le tekanyetso ea ka hare. Ho kopanya ho qalile ka metsi a boima (D₂O) le cyclohexanone, ho tsoela pele ka phapanyetsano ea hydrogen-deuterium e nang le base-catalyzed, reductive amination, le mehato ea sulfonylation ho qetella ho hlahisa tetradeutero sodium cyclohexylsulfamate ka bongata ba deuterium isotope bo fetang 99%. Ha bo sebelisoa hammoho le isotope dilution mass spectrometry (ID-MS), maemo a joalo a ka hare a ntlafatsa haholo ho nepahala le ts'epo ea ho lemoha, haholo-holo bakeng sa netefatso le tekanyo e nepahetseng ea maemo a trace a sodium cyclamate lisampoleng tse rarahaneng.
2. Tlhahlobo botjha ya Ditlamorao tsa Polokeho le Bophelo bo Botle
Polokeho ea sodium cyclamate e ntse e tsoela pele ho ba ntlha ea bohlokoa ea tlhokomelo ea saense le ea sechaba, ka lithuto tse ncha tse ntseng li hlahloba litlamorao tsa eona tse ka bang teng bophelong.
Melao le Tšebeliso ea Hona Joale:
Ho bohlokoa ho hlokomela hore melaoana e laolang sodium cyclamate ha e kopane lefatšeng ka bophara. Tšebeliso ea eona e le sejo se eketsang lijo e thibetsoe linaheng tse kang United States, United Kingdom le Japane. Leha ho le joalo, e lumelloa linaheng tse kang Chaena, leha ho na le meeli e tiileng e phahameng (mohlala, GB2760-2011). Meeli ena e thehiloe ho latela litekolo tse teng tsa polokeho.
Matšoenyeho Mabapi le Likotsi Tse ka Bang Teng Bophelong:
Leha liphetho tsa lipatlisiso li sa ka tsa senola liphetho tse ncha tse kholo ka 2025 mabapi le likotsi tsa bophelo bo botle tse ikhethileng ho sodium cyclamate ka boeona, phuputso mabapi le setlolo se seng sa maiketsetso, sodium saccharin, ea hlokomeleha. Ha ho sebelisoa mohlala oa litoeba tse bakoang ke letrozole oa polycystic ovary syndrome (PCOS), phuputso e fumane hore sodium saccharin e ka mpefatsa lintho tse sa tloaelehang tse amanang le PCOS (mohlala, ho fokotseha ha lisele tsa granulosa tsa kantle, ho eketseha ha li-cyst) le mathata a endocrine ka ho kenya tšebetsong li-receptor tsa tatso e monate le e babang ka har'a mae a bomme, ho sitisa lintlha tsa steroidogenic (joalo ka StAR, CYP11A1, 17β-HSD), le ho kenya tšebetsong tsela ea p38-MAPK/ERK1/2 apoptosis. Patlisiso ena e sebetsa e le khopotso ea hore litlamorao tse ka bang teng tsa bophelo bo botle tsa setlolo sa maiketsetso, haholo-holo ho tsoa ho jeoeng nako e telele le tšusumetso ea sona ho baahi ba itseng ba nang le kutlo, li hloka tlhokomelo e tsoelang pele le thuto e tebileng.
3. Mekhoa ea 'Maraka le Litaelo tsa Nakong e Tlang
'Maraka le nts'etsopele ea sodium cyclamate le tsona li bonts'a mekhoa e itseng.
E susumetsoa ke Tlhoko ea 'Maraka:
Mmaraka oa tsoekere ea maiketsetso, ho kenyeletsoa le sodium cyclamate, o susumetsoa ka karolo e itseng ke tlhoko ea lefats'e e tsoang indastering ea lijo, lino le meriana bakeng sa li-sweeteners tse nang le lik'hilojule tse tlase le tse theko e tlase. Haholo-holo linaheng tse ling tse tsoelang pele, sodium cyclamate e ntse e sebelisoa ka lebaka la theko ea eona e tlase le matla a eona a monate a phahameng (hoo e ka bang makhetlo a 30-40 a monate ho feta sucrose).
Mekhoa ea Nts'etsopele ea Nakong e Tlang:
Ha e tobane le liphephetso, indasteri ea sodium cyclamate e ka 'na ea tsepamisa maikutlo haholoanyane ntlafatsong e shebaneng le bophelo bo botle. Sena se ka kenyelletsa ho hlahloba lintlafatso tsa sebopeho sa limolek'hule le mekhoa ea ho ntlafatsa ho lumellana ha eona le boemo ba tatso, e leng se etsang hore e be haufi le tsoekere ea tlhaho. Ka nako e ts'oanang, ho kopanya mohopolo oa phepo e nepahetseng ho nts'etsapele lihlahisoa tse ikhethileng tse fihlelang litlhoko tse itseng tsa bophelo bo botle (mohlala, taolo ea lefu la tsoekere) le hona ke tataiso e ka bang teng.
Ka kakaretso, tsoelo-pele ea morao-rao ea lipatlisiso mabapi le sodium cyclamate e bonts'a litšobotsi tse peli tsa mantlha:
Ka lehlakoreng le leng, mahlale a ho lemoha a ntse a hatela pele ho ea lebelong le leholo, ho nepahala le ho feta. Mahlale a macha, joalo ka motsoako oa litšoantšo tsa hyperspectral le ho ithuta ha mochini le ts'ebeliso ea litekanyetso tsa ka hare tsa isotope tse tsitsitseng, a fana ka lisebelisoa tse matla haholoanyane bakeng sa taolo ea polokeho ea lijo.
Ka lehlakoreng le leng, ho ntse ho e-na le matšoenyeho mabapi le litlamorao tsa eona bophelong. Leha lintlha tsa morao tjena tsa chefo haholo-holo ho sodium cyclamate ka boeona li lekanyelitsoe, lithuto tse mabapi le lintho tse monate tse entsoeng ka maiketsetso (mohlala, sodium saccharin) li bontša hore ho hlokahala tlhokomelo e tsoelang pele liphellong tsa tsona tsa bophelo bo botle tsa nako e telele.
Nako ea poso: Loetse-15-2025