Theknoloji ea ho Fetola Limolek'hule e Fetola Mokhoa oa Khale oa Lilemo, Theknoloji e nkhang hamonate ea Amine Direct Deamination e Tlisa Phetoho ea Chain ea Liindasteri.

Phahamiso e kholo

Ka la 28 Mphalane, thekenoloji e tobileng ea ts'ebetso ea "deamination functionalization" bakeng sa li-amine tse nkhang hamonate e ntlafalitsoeng ke sehlopha sa Zhang Xiaheng se tsoang Setsing sa Hangzhou sa Advanced Study, University of Chinese Academy of Sciences (HIAS, UCAS) se phatlalalitsoe ho Tlhaho. Theknoloji ena e rarolla mathata a polokeho le litšenyehelo a 'nileng a aparela indasteri ea lik'hemik'hale ka lilemo tse 140.

Lintlha-khōlō Tsa Theknoloji

1.E tlohela mokhoa o tloaelehileng oa letsoai oa diazonium (o atisang ho phatloha le tšilafalo e phahameng), ho finyella phetoho e sebetsang ea CN bond ka N-nitroamine intermediates.
2.Ha e hloke li-catalyst tsa tšepe, ho fokotsa litšenyehelo tsa tlhahiso ka 40% -50%, 'me e qetile ho netefatsa li-kilogram.
3.E sebetsa hoo e batlang e le li-amine tsohle tsa meriana ea heteroaromatic le lihlahisoa tsa aniline, ntle le ho thibeloa ke boemo ba sehlopha sa amino.

Tšusumetso ea Liindasteri

1.Indasteri ea Pharmaceutical: E le skeleton ea bohlokoa ea 70% ea lithethefatsi tse nyenyane tsa molek'hule, motsoako oa li-intermediate bakeng sa lithethefatsi tse thibelang kankere le li-antidepressants li ba tse sireletsehileng le tse nang le chelete e ngata. Likhoebo tse kang Baicheng Pharmaceutical li lebelletsoe ho bona phokotso ea 40% -50%.
2.Indasteri ea Dyestuff: Likhoebo tse etellang pele tse kang Zhejiang Longsheng, tse nang le karolo ea 25% ea 'maraka ka li-amine tse nkhang hamonate, li rarolla kotsi ea ho phatloha e thibelitseng nako e telele katoloso ea bokhoni.
3.Indasteri ea chefo e bolaeang likokoanyana: Likhoebo tse kenyeletsang Yangnong Chemical li tla ba le phokotso e kholo ea litšenyehelo tsa li-intermediate tsa chefo e bolaeang likokoanyana.
4.Lisebelisoa tsa elektronike: E khothalletsa tlhahiso e tala ea lisebelisoa tse khethehileng tse sebetsang.

Karabelo ea Capital Market

Ka la 3 Pulungoana, lekala la lik'hemik'hale le ile la matlafala khahlano le mokhoa oa 'maraka, ka karolo e nkhang hamonate ea amine e etelletseng pele melemo le menahano e amanang le eona e bonts'a matla a felletseng.